ACTA VETERINARIA ET ZOOTECHNICA SINICA ›› 2016, Vol. 47 ›› Issue (8): 1531-1538.doi: 10.11843/j.issn.0366-6964.2016.08.002

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The Key Role of Melanosomes in Melanin Production

DU Zhan-yu 1.2,ZHAO Jia-ping2,SONG Xing-chao2,LI Xue-jiao3,WU Qiong2,YANG Ying2,XING Xiu-mei2,XU Chao 2* ,ZHANG Lin-bo 1*   

  1. (1.Jilin Agricultural University,Changchun 130118,China;2.Key Laboratory of Special Economic Animal Genetic Breeding and Reproduction,Ministry of Agriculture,State Key Laboratory of Special Economic Animal Molecular Biology,Institute of Special Animal and Plant Science,Chinese Academy of Agricultural Sciences,Changchun 130112,China;3.Changchun Changsheng Biotechnology Co.Ltd.,Changchun 130103,China)
  • Received:2016-03-22 Online:2016-08-23 Published:2016-08-23

Abstract:

The melanosomes are the only organelles which synthesize and deposit melanin in eukaryotic cells.The dysfunction of melanosomes will lead to pigment related diseases in human or mammalian.Biogenesis of melanosomes (melanosome formation and maturation,the premelanosome fiber formation and melanosome protein transportation),the balance of melanosome internal environment and melanosome transportation are essential prerequisite for melanin synthesis and deposition.To review the parameters of melanosomes will be helpful to further understand the result of hypopigmentation in mammalian,revealing the human albinism related diseases and providing a theoretical reference.

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